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The effects of high-fat diet on implant osseointegration: an experimental study

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Dundar Serkan, Yaman Ferhan, Ozupek Muhammed Fatih, Saybak Arif, Gul Mehmet, Asutay Fatih, Kirtay Mustafa, Ozercan Ibrahim Hanifi,
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 ( Dundar Serkan ) - Firat University Faculty of Dentistry Department of Periodontology
 ( Yaman Ferhan ) - Dicle University Faculty of Dentistry Department of Oral and Maxillofacial Surgery
 ( Ozupek Muhammed Fatih ) - Inonu University Faculty of Dentistry Department of Oral and Maxillofacial Surgery
 ( Saybak Arif ) - Private Practice Periodontists
 ( Gul Mehmet ) - Dicle University Faculty of Dentistry Department of Periodontology
 ( Asutay Fatih ) - Afyon Kocatepe University Faculty of Dentistry Department of Oral and Maxillofacial Surgery
 ( Kirtay Mustafa ) - Inonu University Faculty of Dentistry Department of Oral and Maxillofacial Surgery
 ( Ozercan Ibrahim Hanifi ) - Firat University Faculty of Medicine Department of Medical Pathology

Abstract


Objectives: In this study, we investigated whether a high-fat diet (HFD) affected the bone implant connection (BIC) in peri-implant bone.

Materials and Methods: Four male rabbits were used in this study. Dental implant surgery was introduced into each tibia, and four implants were integrated into each animal. In both the normal diet (ND) group (n=2) and HFD group (n=2), 8 implants were integrated, for a total of 16 integrated implants. The animals continued with their respective diets for 12 weeks post-surgery. Afterward, the rabbits were sacrificed, and the BIC was assessed histomorphometrically.

Results: Histologic and histomorphometric analyses demonstrated that BIC was not impaired in the HFD group compared to the ND group.

Conclusion: Within the limitations of this study, we found that HFD did not decrease the BIC in rabbit tibias.

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Bone implant contact; Osseointegration; Titanium implants; High-fat diet; Histomorphometric analysis

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